uric acid production - A New Gout Drug. Febuxostat wins marketing approval in the European Union
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A New Gout Drug. Febuxostat wins marketing approval in the European Union

It has taken a very long time for a major new gout drug to be developed and approved. Probably the best gout news in over 40 years, is that Febuxostat, which has been given the trade/brand name of Adenuric, has been approved by the European Medicines Agency for marketing in European Union (EU) countries.


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People Said About Goutezol Gout Relief
"My big toe was in horrible pain, so i went to emergency room. Dr diagnosed gout in my foot and gave me pain killers. I did some googling and found goutezol. I like that it's natural with no chemicals in it. Ive been taking it for about 6 months and so far no attack, and my doc confirmed lower uric acid in my blood. thank you!" Jeff, NY
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 The worst offenders are red meats, offal, processed meats, some shellfish, yeast extracts, gravies and alcohol. All of these encourage uric acid production within the body.

From obesity, we move to related causes of gout, specifically dietary and food habits. There are many types of food that have large amounts of purines, or substances that play a large role in uric acid production. It's kind of disturbing to find out that most foods that are rich in protein and fat also have a high purine content. But in today's fast-paced mode of life, this is just the kind of food that we're accustomed to eating! To further reduce the risk of acquiring gout, one should also refrain from taking in too much organ meats or sweetbread (including heart, kidney, and liver delicacies). Some seafoods, such as scallops, mackerel, and mussels are also dietary no-no's because these too are rich in purines. Intake of high-fat dairy foods should also be curtailed, including comfort foods like ice cream, butter, and cheese.

However, as science leads us to understanding our body more. Simple gout pain treatment remedies have been used since the time of kings (gout is known as the disease of kings) are one of the most effective ways to treat the arthritic pain.

When purine is ingested the waste by-product is uric acid. Purine is found in many of our foods and in all proteins to a greater or lesser degree.

There are other stories of 'miracles' with these products and they will be posted as soon as they can be collected. What these products actually do is work to make your body function the way it is supposed to function, and they accomplish this at least in part by restoring your natural Ph balances.

Though scientists are as yet uncertain about how gout really occurs, they have discovered that the causes of gout can be genetic or environmental in nature, as discussed above. Knowing the things and events that can cause the disease would be a big step in reducing one's risk of acquiring it.

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3. Vitamin C or ascorbic acid has shown to be quite effective. While taken in high doses, vitamin C can decrease uric acid levels in the blood.

7. Finally, we also suggest cherries because they hold loads of fiber (to flush) and they also have been shown to reduce inflammations. This popular but effective alternative remedy for gout has been handed down for thousands of years. We suggest about 8 ounces of cherries per day.

Make sure to go to the product testimonials page above, scroll to the bottom, and click on the email contact for any of the people given, and receive their confirmation and personal full testimonial. Disclaimer: This article in no way should be taken as 'medical advice' on any product, condition or course of action, nor does it constitute in any way 'medical advice' endorsing any specific product, specific result, nor any possible cure for any condition or problem. This article is meant as a source of information upon which you may base your decision as to whether or not you should begin using any vitamin, mineral and/or herbal supplement for better health, or begin using a 'greens' product as a dietary supplement.

This article is Copyright 2005 by http://www.organicgreens.us, http://www.organicgreens.ca and Loring Windblad. This article may be freely copied and used on other web sites only if it is copied complete with all links and text, including the Authors Resource Box, intact and unchanged except for minor improvements.

Gout Cherry Juice is made from Tart Cherries, which contain anthocyanins and flavonoids. These naturally occurring ingredients are what appears to be helping out the gout patients.

BENEFITS In large trials Febuxostat (Adenuric) has outperformed Allopurinol, the most common gout medication for long term treatment. Like Allopurinol, it works to lower uric acid production by inhibiting xanthine oxidase, an enzyme required to produce uric acid. In two major studies it reduced uric acid (UA) in more gout sufferers, and more patients reached the target 6.0 mg/dL level more quickly, than did those on Allopurinol.

Ensure that you are keeping your body sufficiently hydrated by drinking at minimum 6 - 8 eight ounce glasses of water. Dehydration will increase uric acid levels as without enough water uric acid will become more concentrated in the blood and the kidneys will struggle to expel it. By staying hydrated you will dilute the uric acid and the kidneys will have a easier time of the elimination process.

5. One homeopathic remedy is bromelain which is an enzyme. This enzyme is naturally found in pineapple and is a natural anti-inflammatory. You should take 200-300 mg three times per day between meals.

If you are tired of the pain and inflammation and want to get your life back to normal. Please check out our step by step Gout Remedy Report that has helped tens of thousands of sufferers with an extremely-high satisfaction rate.

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On the testimonials page below I am L. Windblad and my wife is J.D. Windblad. I have long-term gout (since 1977), damage from gout including numbness and pain in the feet, a prostate which had ceased functioning for the past 2 years, and in Jan 2004 I was diagnosed with a lazy thyroid. By the end of January my thyroid was functioning normally, by April I was noticing an improvement in prostate functioning and by mid-May it was definitely clear that not only was the pain gone but feeling was coming back into my feet. This is written in June 2004 and its all still getting better.

Overview of Gout Gout is a systemic disease caused by the buildup of uric acid in the joints, causing inflammation, swelling, and pain. This condition can develop for two reasons. The liver may produce more uric acid than the body can excrete in the urine, or a diet of rich foods (e.g., red meat, cream sauces, red wine) puts more uric acid into the bloodstream than the kidneys can filter. In both cases, a condition called hyperuricemia results. Over time, the uric acid crystallizes and settles in the joint spaces, most commonly in the first metatarsal phalangeal joint of the big toe or in the ankle joint. Signs and Symptoms The most common symptoms of gout are inflammation, swelling, and tenderness in the joint of the first toe. Touching or moving it is intensely painful and patients often say it hurts to have as much as a bedsheet over the toe. Gout develops quickly and typically occurs in only one joint at a time. Symptoms may develop in two or three joints simultaneously, but this is rare. If widespread symptoms occur, the condition is probably not gout. Diagnosis The most reliable way to diagnose gout is to examine the joint fluid for uric acid crystals. This is done by drawing fluid from the joint with a needle and examining it under a polarized light microscope. Although the test is invasive, the results are definitive, and a positive result facilitates proper treatment and quick relief. Treatment Treatment for gout involves decreasing the amount of uric acid in the joint. If dietary habits are the cause, the patient's lifestyle must be changed to avoid the condition. Gout is readily corrected with patient cooperation, and it is usually not treated unless it occurs frequently. Colchicine is a common medication for treating acute gout attacks. If continuous medication is necessary, the two most common choices are probenecid and allopurinol. Prevention Alcohol and rich foods are primary contributors to excessive uric acid levels. Although some patients have a genetic predisposition to excessive uric acid production, most gout patients have normal kidneys and uncontrolled dietary habits. Prevention is the best defense against the disease. Many patients who suffer from gout continue to indulge, and suffer frequent attacks as a result. Although medication makes it possible to live with gout, the continued accumulation of uric acid in the joints eventually damages them, seriously inhibiting movement.

It is recommended that NSAIDs or Colchicine are used along with Adenuric. This is because, as with Allopurinol, on a course of Febuxostat, there may be an initial increase in gout flares. If this happens you must battle through the attacks and continue taking Adenuric.

If in doubt, or if you have questions, you should consult your physician and, if possible, consult a second physician for a possible different opinion. The author does not bear any responsibility for your decisions nor for the outcome of your actions based upon those decisions.

Tophi If you have tophi, it's heartening to know that Febuxostat has been shown to have success against tophi. Measured tophi areas reduced in many patients with tophi. The presence of tophi will be an additional factor in favour of a decision to prescribe Febuxostat (Adenuric).

NB. The contents of this article contain medical information not medical advice. Please always discuss remedies with your doctor or other health care professional, before implementing any treatment.

 
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"I was only 30 when I got a gout attack. Goutezol really helped me to get over the attack in just two days and the ebook helps me with watching what I'm eating. My uncle have had gout problems too, so I recommended your product. Thanks a lot!" Matt, California
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Usually, gout is flushed out of the body through the urine. But in certain individuals, gout is caused because the body either produces too much uric acid or your kidneys excrete too little uric acid.

Many gout sufferers have been drinking Gout Cherry Juice and have so far been reporting amazing results. It seems that drinking Gout Cherry Juice on a daily basis has kept numerous sufferers free from attacks. Also, comments from those who have not had daily intakes of the juice have claimed that when an attack starts if they begin to drink the juice, they will immediately notice a reduction in the length of the attack, as well as a great change in the severity of the attacks. These results typically convince them to begin drinking the juice every day.

Check out these product testimonials and see what you think about what these products have accomplished in many other lives. Scroll to the bottom of the page and contact the people who gave these testimonials.

Gout is an affliction usually associated with men over the age of 40, and is a type of arthritis that involves uric acid concentration. Uric acid is a byproduct of the liver process; you need a certain amount of it in your bloodstream. When high concentrations occur, needlelike crystals of monosodium urate form in the bloodstream settling in the joints causing inflammation and pain, which are all symptoms of gout.

Finding a gout free diet may be simpler than you first think and it may surprise you to know that are a surprising number of additional benefits that can be had.

Hyperuricemia is when uric acid levels are too high and can lead to gout and kidney stones. Also, a recent study by doctors at John Hopkins University Hospital found that cognitive functions can be reduced if there is increased Uric Acid in the body. The research was carried out on just under 100 people between the ages of 65 - 92.

Approval in one country does not mean approval in another, but the fact that the European Medicines Agency has approved it will carry weight when the medical authorities in other countries consider its approval.

Gout can also be caused by certain medications, such as thiazide diuretic drugs, which are prescribed for heart failure and hypertension. Figures show that the majority of people who use this kind of drug acquired gout later in life. Other drugs that may contribute to a higher risk for gout are immunosuppressants (such as cyclosporine), low doses of aspirin, and pyrazinamide, an anti-tuberculosis agent. Gout is also strangely related to organ transplantation. Heart and liver transplants can heighten the risk, but perhaps it's a kidney transplant that poses the greater risk, since renal problems can prevent the elimination of uric acid from the body.

Gout is certainly not a fun condition to have. It's a common rheumatic disease and it counts rheumatoid arthritis and osteoarthritis among its close cousins. Figures show that some 840 people out of 100,000 are afflicted with this disease, most of them men. Just what are the causes of gout, and are there any effective ways to avoid it? More often than not, gout is a result of lifestyle choices, but there are other factors that contribute to the disease's occurrence.

Although gout is can be a hereditary condition where the body fails to process uric acid efficiently, you can help your body regain its balance by minimizing external factors that raise uric acid levels. One of the main factors that you can control to alleviate gout is to reduce the levels of purine rich foods consumed.

And it may cause side effects of course. See the bottom of this article. Febuxostat (Adenuric) is not unfortunately a treatment for gout pain. It won't be used instead of NSAIDS like Indomethacin, Colchicine, and corticosteroids.

Sticking to dietary goals while eating out can be very challenging. Many, even most, restaurants cater to people with special dietary needs ' just ask. And learn those restaurants which do not and avoid them.




It will also only be used in gout patients who have chronic hyperuricemia (high UA levels) and gout. So if you're a gout sufferer who lives in a European country that's a member of the EU, you can ask your doctor's opinion about whether Febuxostat is suitable for you.

Long known for their gorgeous bright red color, Tart Cherries are now found to be much, much more than simply a tart and delicious fruit. The relief gout sufferers have noticed upon drinking Gout Cherry Juice has been recorded, and some have even been able to come off of all their medications because of the great changes. The pain associated with gout is a constant menace to those afflicted. Medication is available, and helps, but as with any medication-- there are side effects. For those sufferers willing to change their diet, Gout Cherry Juice can reduce many side effects and do away with them completely in many circumstances.

Generally, Febuxostat has been more effective when UA levels are below 10.0 mg/dL (595 mmol/??mol). However, even if they have been above this level, it has reduced UA levels down to the target in about 40% of study patients at an 80 mg dosage, and by more at higher dosages.

Scientists are now beginning to explore the effects of anthocyanins and flavonoids on uric acid production. The Medical Universities are putting out more concrete evidence continually, concerning the health benefits associated with these Tart Cherries. Gout Cherry Juice is made from these Tart Cherries, and the comments from users are showing that the benefits drawn from the juice can relieve the pain and inflammation associated with gout, pleasing many people who are afflicted with the disease. It is always recommended to check with your doctor before discontinuing medication, or making large changes in your diet. For more information about Gout Diet?, feel free to visit us at: http://www.about-goat.info/Articles/Gout_Diet.php

At 120 mg it has reduced UA levels to the target of 6.0 mg/dL in over 60% of study patients. At 80 mg the numbers were around 51%. Allopurinol at a 300 mg dosage in most participants achieved this is 22% of study patients. Hence the excited buzz in rheumatology circles since these kinds of results became apparent in its trials. At or below 6.0 mg/dL gout is more likely to be cured or managed better.

Your uric acid levels will have to be high. If you have gout but normal or slightly raised uric acid levels as some do, it is unlikely to be prescribed.

Alcoholic beverages should strictly be avoided or at least restricted to an occasional glass or two. This is because alcohol has a high purine concentration and contributes in significant ways to the body's production of uric acid. Not only does it spur the body on to produce more uric acid, but it also affects the ability of the kidneys to flush out excess amounts of this substance. Plus, alcohol is fattening, and we know that surplus weight can also lead to gout.

A condition called hyperuricemia is one of the causes of gout. This is when the body fails to eliminate excess amounts of uric acid. Some people are born with a genetic metabolic defect in which they not only produce extra uric acid, but they fail to excrete it efficiently as well. This is bad because excessive amounts of uric acid will lead to the formation of uric crystals, which will then become embedded in the joints and the tissue surrounding them. These crystals are also known as tophi, and they are the cause of joint inflammation and pain. Gout usually appears in the joint of the big toe, but it can also become manifest in joints in the ankles, feet, knees, wrists, hands, and elbows. Pictures of a gouty toe almost always show the same characteristics: swelling and redness, and as you can probably imagine, pain.

A number of health problems have been shown to lead to gout. Certain cancers or diseases involving blood-manufacturing organs are specifically cited, such as lymphoma and leukemia. A skin disease called psoriasis has likewise been linked to the emergence of gout in a number of people. And over-exposure to lead does not only cause birth defects and blood poisoning, it can lead to gout as well. Another all too common health problem among many people, especially those in the West, is obesity. Being overweight can cause not only gout, but other diseases as well, including diabetes, hypertension, and other forms of arthritis.

You will not need to be on a low purine diet, and more good news is that it can be prescribed for the elderly. Kidney and liver disease In trials it has performed quite well with patients who have mild kidney disease. 44% of patients achieved the target at an 80 mg dosage, more at higher dosages. Better results than Allopurinol. If you have mild kidney disease (renal impairment) or mild liver problems (hepatic impairment) your doctor will judge whether Adenuric/Febuxostat can be taken safely.

This approval applies only to EU countries. Febuxostat has not yet been approved in the United States. If you are reading this from a non-EU country, or the US, you can check with your doctor to find out whether, or when, Febuxostat will be approved in your country.

What you may not know about diabetes ' the truth about insulin resistance. 92% of people with type 2 diabetes have insulin resistance. Get the facts ' go to your local diabetes agency or research it on the internet.


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One last thought, a gout free diet does not need to be boring many herbs and spices, and healthy options are available to make tasty and nutritious meals that won't aggravate your gout.


 
 
     
 
 





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